A four-time Emmy winner for Best Supporting Actor in a Comedy Series, Larroquette is also an avid collector of more than 2,000 modern first edition books, as well as antique fountain pens, cameras, photographs, and watches.

Larroquette is perhaps best known to television audiences as Assistant District Attorney Dan Fielding, a role he played on NBC's Night Court. He also starred in the NBC comedy series The John Larroquette Show, for which he was nominated for an Emmy Award in the show's second season.

Larroquette won his fifth Emmy in 1998 as a guest-star in two episodes of the drama The Practice. He portrayed a homosexual who murdered his lover. He was also seen in another dramatic role in Showtime's The Defenders, a courtroom drama based on a series that ran from 1961-1965 on CBS. Larroquette portrayed a man who was charged with murder for killing his daughter's rapist.